Anti-EIF2AK2 (pThr446) Antibody (A283733)

Anti-EIF2AK2 (pThr446) Antibody

Rabbit anti EIF2AK2 (pThr446)

Rabbit anti EIF2AK2 (pThr446) antibody recognizes interferon-induced, double-stranded RNA-activated protein kinase when phosphorylated on threonine 446. EIF2AK2 is a serine/threonine protein kinase which is activated by double-stranded RNA (dsRNA) and phosphorylates the a subunit of eukaryotic initiation factor 2 (eIF2a) (Hershey 1991). EIF2AK2 is induced by kisspeptin and its activation inhibits cancer growth (Kim and Cho 2017). Autophosphorylation of EIF2AK2 at threonine 446 is critical for kinase activity (Zhang et al. 2001).

Human

Phospho specific-peptide corresponding to residues surrounding serine threonine 446 of human EIF2AK2.

Rabbit

Polyclonal

Affinity chromatography.

Liquid

Supplied in Phosphate Buffered Saline with 50% Glycerol and < 0.1% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.