Anti-ELF1 Antibody (A320094)

Anti-ELF1 Antibody

Goat polyclonal antibody to ELF1.

This antibody recognises ETS-related transcription factor Elf-1, also known as E74-like factor 1 (ELF1).ELF1 is a small zinc-finger protein conserved in eukaryotes and some archaea. ELF1 is ubiquitously expressed in human cells and is a member of the ETS family of transcription factors and appears to act downstream of the DNA damage response pathway. In cancer, ELF1 appears to have oncogenic and tumor suppressive functions depending on context. ELF1 appears to play an antiviral role, with lower levels of ELF1 reducing host defense against the influenza A virus.

WB, IHC-P

IHC-P: 2.5 µg/ml, WB: 0.03 µg/ml - 0.1 µg/ml

Human, Mouse

A peptide sequence of C-AMKQNELLEPNSF from the C-terminus of the protein sequence according to NP_758961.1; NP_001138825.1.

C-AMKQNELLEPNSF

Goat

Polyclonal

IgG

500 µg/ml

Approximately 70 kDa in cell lysates

Liquid

Supplied in TRIS Buffered Saline, 0.5% BSA and 0.02% Sodium Azide.

Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Goat anti ELF1 antibody recognizes ETS-related transcription factor Elf-1, also known as E74-like factor 1 (ELF1).ELF1 is a small zinc-finger protein conserved in eukaryotes and some archaea (Ehara and Sekine 2018). ELF1 is ubiquitously expressed in human cells and is a member of the ETS family of transcription factors (Budka et al. 2018) and appears to act downstream of the DNA damage response pathway (Cheng et al. 2020). In cancer, ELF1 appears to have oncogenic and tumor suppressive functions depending on context (Budka et al. 2018). ELF1 appears to play an antiviral role, with lower levels of ELF1 reducing host defense against the influenza A virus (Seifert et al. 2019).

E74-like factor 1, ETS-related transcription factor Elf-1