Anti-EMR3 Antibody [3D7] (FITC) (A279300)

Anti-EMR3 Antibody [3D7] (FITC)

Hamster monoclonal [3D7] antibody to EMR3 (FITC).

This antibody recognises human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), a ~56 kDa member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. EMR3 is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. EMR3 is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells.

Flow Cytometry: Neat - 1:10, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Human

ARHO-EMR3-CD97 (EGF1) transfectants.

Hamster

Monoclonal

3D7

Protein G affinity chromatography of tissue culture supernatant.

100 µg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. This product is photosensitive and should be protected from light.

Hamster anti Human EMR3 antibody, clone 3D7 recognizes human epidermal growth factor (EGF) module-containing mucin-like hormone receptor 3 (EMR3), a ~56 kDa member of the EGF-7 transmembrane (TM7) family of adhesion receptors. EMR3 is expressed at the cell surface as a heterodimer. EMR3 is predominantly expressed on granulocytes, and at lower levels on mature myeloid cells, monocytes and dendritic cells. EMR3 is absent on lymphocytes, haematopoietic stem cells and myeloid progenitors. EMR3 is up-regulated during late stages of neutrophil differentiation and is a marker for terminally differentiated cells (Matmati et al.2007).

ADGRE3, Adhesion G protein-coupled receptor E3, EGF-like module receptor 3, EGF-like module-containing mucin-like hormone receptor-like 3

This product is for research use only. It is not intended for diagnostic or therapeutic use.