Anti-FOXL2 Antibody (A320112)

Anti-FOXL2 Antibody

Rabbit polyclonal antibody to FOXL2.

This antibody recognises forkhead box protein L2.FOXL2 is a 39 kDa transcription factor that belongs to the forkhead box (FOX) superfamily. This family of proteins is characterized by the forkhead box/winged-helix DNA-binding domain. FOXL2 plays an important role in the development and function of ovaries and inhibits the formation of testes via suppression of SOX9 expression. FOXL2 expression levels have been shown to play a role in the development of a number of pathologies, including adult granulosa cell tumors and endometriosis.

WB: 1:500 - 1:1,000

Human

A peptide derived from within the N-terminus of human FOXL2.

Rabbit

Polyclonal

IgG

Liquid

Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human FOXL2 antibody recognizes forkhead box protein L2.FOXL2 is a39 kDa transcription factorthat belongs to theforkheadbox (FOX) superfamily. This family of proteins is characterized by the forkhead box/winged-helixDNA-binding domain. FOXL2 plays an important role in the development and function of ovaries and inhibits the formation of testes via suppression of SOX9 expression (Yang et al. 2017). FOXL2 expression levels have been shown to play a role in the development of a number of pathologies, including adult granulosa cell tumors and endometriosis (Leung et al. 2016) (Governini et al. 2014).

Forkhead box protein L2