Anti-GAB1 Antibody [F01/9A4-2] (A320314)

Anti-GAB1 Antibody [F01/9A4-2]

Mouse monoclonal [F01/9A4-2] antibody to GAB1.

This antibody recognises GRB2-associated-binding protein 1, also known as GAB1, GRB2-associated binder 1 or Growth factor receptor bound protein 2-associated protein 1 when phosphorylated at tyrosine 627.GAB1 is a docking protein capable of interactions with several different proteins particularly the activation of receptor tyrosine kinase signaling. Phosphorylation of GAB1 at tyrosine 627 leads to SHP2 recruitment and subsequent activation of MAPK signaling.

WB: 1:1,000

Human

E. coli derived recombinant protein corresponding to amino acids 243-694 of human GAB1.

DSPPSRAPSASVDSSLYNLPRSYSHDVLPKVSPSSTEADGELYVFNTPSGTSSVETQMRHVSISYDIPPTPGNTYQIPRTFPEGTLGQTSKLDTIPDIPPPRPPKPHPAHDRSPVETCSIPRTASDTDSSYCIPTAGMSPSRSNTISTVDLNKLRKDASSQDCYDIPRAFPSDRSSSLEGFHNHFKVKNVLTVGSVSSEELDENYVPMNPNSPPRQHSSSFTEPIQEANYVPMTPGTFDFSSFGMQVPPPAHMGFRSSPKTPPRRPVPVADCEPPPVDRNLKPDRKVKPAPLEIKPLPEWEELQAPVRSPITRSFARDSSRFPMSPRPDSVHSTTSSSDSHDSEENYVPMNPNLSSEDPNLFGSNSLDGGSSPMIKPKGDKQVEYLDLDLDSGKSTPPRKQKSSGSGSSVADERVDYVVVDQQKTLALKSTREAWTDGRQSTESETPAKSVK

Mouse

Monoclonal

F01/9A4-2

IgG1

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Approximately 102 kDa in HepG2 cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti human GAB1 antibody, clone F01/9A4-2 recognizes GRB2-associated-binding protein 1, also known as GAB1, GRB2-associated binder 1 or Growth factor receptor bound protein 2-associated protein 1 when phosphorylated at tyrosine 627.GAB1 is a docking protein capable of interactions with several different proteins particularly the activation of receptor tyrosine kinase signaling. Phosphorylation of GAB1 at tyrosine 627 leads to SHP2 recruitment and subsequent activation of MAPK signaling.

GRB2-associated binder 1, GRB2-associated-binding protein 1, Growth factor receptor bound protein 2-associated protein 1