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Anti-Glutamate Receptor 1 (AMPA subtype) (phospho Ser831) Antibody (A283961)

This product is discontinued

Anti-Glutamate Receptor 1 (AMPA subtype) (phospho Ser831) Antibody (A283961) has been discontinued and is no longer available.

View all Primary Antibodies.

Name
Anti-Glutamate Receptor 1 (AMPA subtype) (phospho Ser831) Antibody
Description
Rabbit polyclonal antibody to Glutamate Receptor 1 (AMPA subtype) (phospho Ser831).
Specificity
This antibody recognises glutamate receptor 1 (GluR1), also known as AMPA-selective glutamate receptor 1, GluR-A, GluR-K1 and glutamate receptor ionotropic , AMPA 1 (GluA1), when phosphorylated at serine 831.GluR1, widely expressed throughout the nervous system is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses.Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
Applications
WB
Dilutions
WB: 1:1,000
Reactivity
Rat, Mouse, Dog, Human, Chicken
Immunogen
Synthetic phosphopeptide corresponding to an amino acid sequence within GluR1 which includes the phosphorylated residue Ser831.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
Lot Specific
Molecular Weight
Approximately 100 kDa in rat brain lysates.
Product Form
Liquid
Formulation
Supplied in 10mM HEPES, pH 7.5, with 0.01% BSA, 50% Glycerol, and 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Rat GluR1 (pSer831) antibody recognizes glutamate receptor 1 (GluR1), also known as AMPA-selective glutamate receptor 1, GluR-A, GluR-K1 and glutamate receptor ionotropic , AMPA 1 (GluA1), when phosphorylated at serine 831.GluR1, widely expressed throughout the nervous system is a component of AMPA receptors (alpha-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid receptors), which play a key role at excitatory synapses.Phosphorylation of Ser831 and Ser845 is reported to potentiate GluR1 function, suggesting a possible role in synaptic plasticity, learning and memory.
Synonyms
GLUR 1, GLUR A, AMPA 1, AMPA selective glutamate receptor 1, AMPA-selective glutamate receptor 1, GluA1, GLUH1, GluR K1, GluR-1, GluR-A, GluR-K1, GLUR1, GLURA, GluRK1, Glutamate receptor 1, Glutamate receptor ionotropic, Glutamate receptor ionotropic AMPA 1, Glutamate receptor, ionotropic, AMPA 1, Gria1, GRIA1_HUMAN, HBGR1, MGC133252, OTTHUMP00000160643, OTTHUMP00000165781, OTTHUMP00000224241, OTTHUMP00000224242, OTTHUMP00000224243
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.

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