Recombinant Anti-Glycophorin A Antibody [rGYPA/8948] (A315034)

Anti-Glycophorin A Antibody [rGYPA/8948]

Recombinant mouse monoclonal [rGYPA/8948] antibody to Glycophorin A.

Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

K562 cells. Erythrocytes in any human tissues

IHC: 1-2 µg/ml

Human

Recombinant fragment of human glycophorin A protein. The exact sequence is proprietary.

Mouse

Monoclonal

rGYPA/8948

kappa

Protein A/G chromatography.

200 µg/ml

39 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD235a, Glycophorin-A, GPA, GYPA, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha