Anti-GPRC5A Antibody [GPRC5A/7893] - BSA and Azide free (A316432)

Anti-GPRC5A Antibody [GPRC5A/7893] - BSA and Azide free

Mouse monoclonal [GPRC5A/7893] antibody to GPRC5A.

Retinoic acid-induced protein 3 (RAI3) is an transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis, cell growth, differentiation, and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, and selective suppression of signals from RAI3 may have a place in breast cancer treatments.

Expressed at high level in fetal and adult lung tissues. Constitutively expressed in fetal kidney and adult placenta, kidney, prostate, testis, ovary, small intestine, colon, stomach, and spinal chord at low to moderate levels.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 200-357) of human GPRC5A protein. The exact sequence is proprietary.

Mouse

Monoclonal

GPRC5A/7893

kappa

Protein A/G chromatography.

1 mg/ml

32 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

G-protein coupled receptor family C group 5 member A, GPCR5A, PEIG-1, Phorbol ester induced gene 1, RAI3, RAIG-1, RAIG1, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3