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Anti-HIF-1 beta Antibody (A283443)

This product is discontinued

Anti-HIF-1 beta Antibody (A283443) has been discontinued and is no longer available.

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Name
Anti-HIF-1 beta Antibody
Description
Rabbit polyclonal antibody to HIF-1 beta.
Specificity
This antibody recognises aryl hydrocarbon receptor nuclear translocator (encoded by the gene ARNT), also known as hypoxia-inducible factor 1-beta (HIF1-beta) or bHLHe2. ARNT is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. ARNT forms complexes with either hypoxia-inducible factor 1-alpha (HIF-1 alpha) or aryl hydrocarbon receptor (AhR), ARNT is involved in the adaptive response to stress caused by dioxins and hypoxia.
Applications
WB
Dilutions
WB: 1:500 - 1:2,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human ARNT.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate

Unconjugated

Concentration
Lot Specific
Molecular Weight
Approximately 87 kDa in cell lysates under reducing conditions. Rabbit anti ARNT antibody also appears to detect a modified form of ARNT at a higher molecular weight.
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti ARNT antibody recognizes aryl hydrocarbon receptor nuclear translocator (encoded by the gene ARNT), also known as hypoxia-inducible factor 1-beta (HIF1-beta) or bHLHe2. ARNT is a member of the bHLH PAS (basic helix-loop-helix Per-ARNT-Sim) family of transcription factors. ARNT forms complexes with either hypoxia-inducible factor 1-alpha (HIF-1 alpha) or aryl hydrocarbon receptor (AhR), ARNT is involved in the adaptive response to stress caused by dioxins and hypoxia.
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.