Anti-HLA DRB Antibody [Bra30] (A248857)

Anti-HLA DRB Antibody [Bra30]

Mouse monoclonal [Bra30] antibody to HLA DRB.

This antibody reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.

Flow Cytometry, IF

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml

Human, Baboon, Chimpanzee, Monkey, Squirrel, Canine

Human REH cells (non-T, non-B leukemia cell line).

Mouse

Monoclonal

Bra30

IgG2a

kappa

Protein A/G chromatography.

200 µg/ml

~28 kDa (beta chain)

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-HLA DRB Antibody [Bra30] - BSA and Azide free (A252037).