Anti-ICAM2 Antibody [mIC2/4 (3C4)] - BSA and Azide free
Description
Rat monoclonal [mIC2/4 (3C4)] antibody to ICAM2.
Specificity
This antibody recognises mouse intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.Rat anti Mouse CD102 antibody, clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1 (Xuet al. 1996).
Applications
IP, Flow Cytometry, Functional Assays
Dilutions
Flow Cytometry: 1:50 - 1:200, Use 10µl of the suggested working dilution to label 106cells in 100µl
Reactivity
Mouse
Immunogen
COS cells transfected with mouse ICAM-2.
Host
Rat
Clonality
Monoclonal
Clone ID
mIC2/4 (3C4)
Isotype
IgG2a
Conjugate
Unconjugated
Purification
Protein G affinity chromatography of tissue culture supernatant.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline.
Storage
Store undiluted at -20°C only. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rat anti Mouse CD102 antibody, clone mIC2/4 (3C4) recognizes murine intercellular adhesion molecule-2 (ICAM-2), also known as CD102. Murine CD102 is a glycosylated cell surface protein that is broadly expressed on most leucocytes and is constitutively expressed on endothelial cells. CD102 interacts with the CD11a/CD18 integrin LFA-1. Reports suggest that CD102 may play a role in lymphocyte re-circulation and T-cell activation.Rat anti Mouse CD102 antibody, clone mIC2/4 is reported to inhibit interactions between CD102 and LFA-1 (Xuet al. 1996).
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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