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Anti-IDO2 Antibody [IDO2/2639] - BSA and Azide free (A278165)

Mouse monoclonal [IDO2/2639] antibody to IDO2 for ELISA and IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-IDO2 Antibody [IDO2/2639] - BSA and Azide free
Description
Mouse monoclonal [IDO2/2639] antibody to IDO2.
Specificity
IDO2 is a presumptive immunomodulatory gene based on its close structural relationship to IDO1 and its expression in a variety of antigen-presenting cell types. Both IDO1 and IDO2 will catabolize tryptophan to kynurenine. Biochemical studies indicate that both enzymes are similarly robust in catabolic activity, although the in vitro conditions required for IDO2 to manifest the same level of activity differ somewhat from IDO1. However, whether IDO2 is active as a tryptophan catabolizing enzyme in human dendritic cells has been disputed. Further work is needed to conclusively determine that IDO1 and IDO2 are similar in their preference for substrates and reaction pathways to generate product. A non-redundant function for IDO2 relative to IDO1 is suggested by their rather distinct expression patterns and response to extracellular stimuli.
Applications
ELISA, IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 200-350, of human IDO2 protein. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
IDO2/2639
Isotype
IgG
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
47 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IDO2 Antibody [IDO2/2639] (A277577).
Synonyms
IDO-2, INDOL1, Indoleamine 2,3-dioxygenase 2, Indoleamine 2,3-dioxygenase-like protein 1, Indoleamine-pyrrole 2,3-dioxygenase-like protein 1
Isotype Controls
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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Proteins predicted to interact with IDO2

Predicted protein interactions based upon String database. Revelancy score correlates with probability of interaction.
99.5% Relevancy Score
95.3% Relevancy Score
95.2% Relevancy Score
95% Relevancy Score
94.2% Relevancy Score
93.8% Relevancy Score
93.7% Relevancy Score
93.3% Relevancy Score