Anti-IL-1RA Antibody [IL1RA/4715] (A315160)

Anti-IL-1RA Antibody [IL1RA/4715]

Mouse monoclonal [IL1RA/4715] antibody to IL-1RA.

Two forms of interleukin-1, designated IL-1a and IL-1 binding to interleukin receptors. By neutralizing the activity of IL-1, IL-1ra contributes to the inhibition of the immune and inflammatory responses and has been targeted as a drug for the treatment of severely active rheumatoid arthritis. There are four isoforms of IL-1ra that are produced as a result of alternative splicing events.

Epithelial cells.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human Interleukin-1RA protein. The exact sequence is proprietary.

Mouse

Monoclonal

IL1RA/4715

kappa

Protein A/G chromatography.

200 µg/ml

17-25 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

ICIL-1RA, IL-1RN, IL1 inhibitor, IL1F3, IL1RA, IL1RN, Interleukin-1 receptor antagonist protein, IRAP