Anti-IL-22RA1 Antibody (A283236)

Anti-IL-22RA1 Antibody

Goat polyclonal antibody to IL-22RA1.

This antibody recognises an epitope within the N-terminal region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway. IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).

IHC-P, ELISA, IF

ELISA: 1:50,000, IF: 1:100, IHC-P: 1:150

Human

Synthetic peptide sequence DSGPEGTPDTVYSIEYKTYGERDWVAKKG corresponding to amino acids 42-70 within the N-terminus of human IL-22 receptor.

DSGPEGTPDTVYSIEYKTYGERDWVAKKG

Goat

Polyclonal

IgG

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Goat anti Human Interleukin-22 Receptor (N-Terminal) antibody specifically recognizes an epitope within the N-terminal (NT) region of human interleukin-22 receptor (IL-22R), also known as IL-22R alpha-1 (IL22RA1), a member of the type II cytokine receptor family, which signals via the JAK-STAT signalling pathway. IL-22R acts as the functional receptor for IL-22, through association with the beta chain of the IL-10R, and as a receptor for IL-20 and IL-24 through association with the beta chain of IL-20R. Binding of IL-22 to functional IL-22R can be blocked by a soluble form of the receptor known as IL22 binding protein (IL22BP).

CRF2-9, Cytokine receptor class-II member 9, Cytokine receptor family 2 member 9, IL-22 receptor subunit alpha-1, IL-22R-alpha-1, IL22R, IL22RA1, Interleukin-22 receptor subunit alpha-1, ZcytoR11