Anti-IL-28A Antibody [G04-5A2] (A280492)

Anti-IL-28A Antibody [G04-5A2]

Mouse monoclonal [G04-5A2] antibody to IL-28A.

This antibody recognises interleukin-28A (IL-28A), also known as interferon lambda-2 (IFNL2). IL-28A is a member of the IL-10 interferon cytokine family. Similar to interferons, IL-28A is induced by viral infection and has anti-viral activity. IL-28A can be produced by virus infected cells in the skin, leading to upregulation of proteins that inhibit virus replication. In this way, IL-28A may be involved with clearance of viruses in the skin. IL-28A is able to induce the innate and adaptive immune responses to engage in anti-tumor activity. The purified Mouse anti Human interleukin-28A antibody, clone G04-5A2 (MCA6210GA) can be used as a capture antibody in a sandwich ELISA with biotinylated Mouse anti Human interleukin-28A antibody, clone G02-3A6 (MCA6211B) as the detection antibody.

ELISA: 1 µg/ml

Human

E. coli derived recombinant human full length interleukin-28a (Val26-Val200).

Mouse

Monoclonal

G04-5A2

IgG1

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human interleukin-28A antibody, clone G04-5A2, recognizes interleukin-28A (IL-28A), also known as interferon lambda-2 (IFNL2). IL-28A is a member of the IL-10 interferon cytokine family. Similar to interferons, IL-28A is induced by viral infection and has anti-viral activity (Kempuraj et al. 2004). IL-28A can be produced by virus infected cells in the skin, leading to upregulation of proteins that inhibit virus replication. In this way, IL-28A may be involved with clearance of viruses in the skin (Wolk et al. 2010). IL-28A is able to induce the innate and adaptive immune responses to engage in anti-tumor activity (Numasaki et al. 2007).The purified Mouse anti Human interleukin-28A antibody, clone G04-5A2 (MCA6210GA) can be used as a capture antibody in a sandwich ELISA with biotinylated Mouse anti Human interleukin-28A antibody, clone G02-3A6 (MCA6211B) as the detection antibody.

Cytokine Zcyto20, IFN-lambda-2, IFNL2, IL28A, Interferon lambda-2, Interleukin-28A, ZCYTO20