Anti-IL-36 gamma / IL-1F9 Antibody - BSA and Azide free (A283750)

Anti-IL-36 gamma / IL-1F9 Antibody - BSA and Azide free

Rabbit polyclonal antibody to IL-36 gamma / IL-1F9.

This antibody recognises interleukin-36 gamma (IL-36 gamma) also known as IL-1 related protein 2, IL-1 epsilon, IL-1 family member 9 and IL-1 homologue 1. IL-36 gamma is a member of the IL-1 superfamily of cytokines and elicits its biological function through the IL-1 receptor-related protein 2. Activation of this receptor can lead to the activation of the NF-?B, MAPK, JNK and ERK signaling cascades. In this way, IL-36 gamma is able to act as a proinflammatory cytokine, with the exact biological function dependent on the type and site of inflammation.

WB, ELISA

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Human

E. coli derived recombinant human interleukin-36 gamma.

Rabbit

Polyclonal

IgG

Lyophilized

Reconstitute with 0.1 ml of distilled water.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human interleukin-36 gamma antibody, recognizes interleukin-36 gamma (IL-36 gamma) also known as IL-1 related protein 2, IL-1 epsilon, IL-1 family member 9 and IL-1 homologue 1. IL-36 gamma is a member of the IL-1 superfamily of cytokines and elicits its biological function through the IL-1 receptor-related protein 2. Activation of this receptor can lead to the activation of the NF-?B, MAPK, JNK and ERK signaling cascades (Bao et al. 2020). In this way, IL-36 gamma is able to act as a proinflammatory cytokine, with the exact biological function dependent on the type and site of inflammation (Ding et al. 2017).