Anti-IL10RA Antibody [1B1.3a] - BSA and Azide free (A254211)

Anti-IL10RA Antibody [1B1.3a] - BSA and Azide free

Rat monoclonal [1B1.3a] antibody to IL10RA.

This antibody recognizes Mouse Interleukin-10 receptor 1 (IL-10R1), a cell surface glycoprotein of approximately 110KDa. Its epitope is localized in the ligand-binding domain in the extracellular region of Mouse IL-10R1. This antibody blocks the binding of IL-10 to its receptor. IL-10R1 is a class II cytokine receptor expressed on thymocytes, T cells, B cells, NK cells, monocytes and macrophages. Binding of IL-10 to its receptor initiates JAK/STAT signaling that leads to B cell proliferation and inhibition of macrophage activation.

Neutralization Studies, Flow Cytometry, IF

Flow Cytometry: 0.5-1 µg/million cells, IF: 1-2 µg/ml

Mouse

This antibody does not cross react with Human.

Recombinant extracellular region of mouse IL10RA.

Rat

Monoclonal

1B1.3a

IgG1

Protein A/G chromatography.

1 mg/ml

90-110 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-IL10RA Antibody [1B1.3a] (A251032).

CD210, CDw210a, IL-10 receptor subunit alpha, IL-10R subunit 1, IL-10R subunit alpha, IL-10R1, IL10R, Interleukin-10 receptor subunit 1, Interleukin-10 receptor subunit alpha