Mouse monoclonal [P1F6] antibody to Integrin alpha V beta 5.
Specificity
This antibody recognises the integrin alpha V beta 5 holomolecule. ITGaVb5 acts as a receptor for fibronectin and has also been co-opted as a cellular receptor for adenovirus type C.
Applications
IF, IP, Flow Cytometry, IHC-Fr, ELISA
Dilutions
For use on human carcinomas, normal epithelium and keratinocytes using acetone or paraformaldehyde fixed tissue sections.
Reactivity
Human, Chicken
Immunogen
Human UCLA P3 cells (lung carcinoma).
Host
Mouse
Clonality
Monoclonal
Clone ID
P1F6
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A affinity chromatography of ascites.
Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Human integrin alpha V beta 5 antibody, clone P1F6 recognizes the integrin alpha V beta 5 holomolecule. ITGaVb5 acts as a receptor for fibronectin and has also been co-opted as a cellular receptor for adenovirus type C (Lyle and McCormick 2010).
