Anti-JAM-C Antibody [CRAM-18 F26] (A280137)

Anti-JAM-C Antibody [CRAM-18 F26]

Rat monoclonal [CRAM-18 F26] antibody to JAM-C.

This antibody recognises mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.JAM-C is expressed at junctions between endothelial and epithelial cells, as well as on leukocytes, platelets, vascular smooth muscle cells and fibroblasts, amongst other cell types. It plays a role in tight junctions and inflammatory processes and interacts with JAM-A and JAM-B.Clone CRAM-18 F26 has been reported to inhibit transendothelial migration (Johnson-Léger et al. 2002).

IF, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:10 - 1:25, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Mouse, Human

Recombinant soluble JAM-C.

Rat

Monoclonal

CRAM-18 F26

IgG2a

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Mouse JAM-c antibody, clone CRAM-18 F26 recognizes mouse and human Junctional adhesion molecule C (JAM-C), also known as JAM-3 and, historically, as JAM-2.JAM-C is expressed at junctions between endothelial and epithelial cells, as well as on leukocytes, platelets, vascular smooth muscle cells and fibroblasts, amongst other cell types. It plays a role in tight junctions and inflammatory processes and interacts with JAM-A and JAM-B.Clone CRAM-18 F26 has been reported to inhibit transendothelial migration (Johnson-Léger et al. 2002).

JAM-2, JAM-3, JAM3, Junctional adhesion molecule 3, Junctional adhesion molecule C