Recombinant rabbit monoclonal [KRTL/7784R] antibody to Keratin 77.
Specificity
The keratins are the typical intermediate filament proteins of epithelia, showing an outstanding degree of molecular diversity. Heteropolymeric filaments are formed by pairing of type I and type II molecules. In humans 54 functional keratin genes exist. They are expressed in highly specific patterns related to the epithelial type and stage of cellular differentiation.This antibody can detect high molecular weight CK10, CK14, CK15 and CK16 and low molecular weight CK19. It usually used in a cytokeratin cocktail with type II cytokeratin antibody.
Applications
IHC-P
Positive Control
Skin or squamous cell carcinoma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human
Immunogen
Synthetic peptide corresponding to Type I Cytokeratins residues within aa100-200 of Type I Cytokeratins.
Host
Rabbit
Clonality
Monoclonal
Clone ID
KRTL/7784R
Isotype
IgG
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
60 kDa / 53 kDa / 51 kDa / 45 kDa / 40 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
CK-1B, Cytokeratin-1B, K77, Keratin, type II cytoskeletal 1b, Keratin-77, KRT1B, KRT77, Type-II keratin Kb39
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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