Anti-Kinesin Heavy Chain Antibody [H2] (A280538)

Anti-Kinesin Heavy Chain Antibody [H2]

Mouse monoclonal [H2] antibody to Kinesin Heavy Chain.

This antibody recognises the heavy chain of kinesin toward the N-terminus. The epitope is located in the region of amino acids 420-445.Kinesins are microtubule associated motor proteins, responsible for converting nucleoside triphosphate released energy into mechanical energy. Kinesin-1 exists as a homodimer of 120-130 kDa chains, known as heavy chains. Associated with this dimer when purified from brain homogenates are light chains of 60-70 kDa. The light chains are involved in binding of kinesin to organelles and appear to have regulatory functions. They are not essential for motility generation.

ELISA, IHC-Fr, WB, IHC-P, IP

WB: 1:500

Bovine, Mammals, Chicken, Invertebrates

Bovine brain kinesin.

Mouse

Monoclonal

H2

IgG2b

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Kinesin Heavy Chain antibody, clone H2 recognises the heavy chain of kinesin toward the N-terminus. The epitope is located in the region of amino acids 420-445.Kinesins are microtubule associated motor proteins, responsible for converting nucleoside triphosphate released energy into mechanical energy. Kinesin-1 exists as a homodimer of 120-130 kDa chains, known as heavy chains. Associated with this dimer when purified from brain homogenates are light chains of 60-70 kDa. The light chains are involved in binding of kinesin to organelles and appear to have regulatory functions. They are not essential for motility generation.