Specificity
Rabbit anti MEK 3 (pSer189) antibody recognizes MAPK/ERK kinase 3 (MEK 3), also known as dual specificity mitogen-activated protein kinase kinase 3, MAP kinase kinase 3 (MAPKK 3) and stress-activated protein kinase kinase 2, when phosphorylated at serine 189.MEK 3 is a dual specificity protein kinase and a member of the MAP kinase family. MEK 3 plays a key role in the MAP kinase signaling pathway. MEK 3 is activated by phosphorylation at serine 189 (Zanke et al. 1996) leading to phosphorylation on downstream targets including p38 MAPK.
