Recombinant rabbit monoclonal [MSLN/6443R] antibody to Mesothelin.
Specificity
Mesothelin is a 40kDa glycosyl-phosphatidylinositol-anchored glycoprotein cleaved from a 69kDa precursor protein. Mesothelin immunoreactivity is high in cancers of the ovary (serous papillary, endometrioid and undifferentiated) and pancreas, with less frequent staining seen in adenocarcinomas of the endometrium, lung and stomach/esophagus. Mesothelin is one of the most sensitive markers for mesothelioma.
Applications
IHC-P
Positive Control
CAPAN-2 or HeLa cells. Lung Mesothelioma.
Dilutions
IHC: 1-2 µg/ml
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fragment (around Amino Acids 273-407) of human Mesothelin (MSLN) protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
MSLN/6443R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
40 kDa (Mature form) / 69 kDa (Precursor)
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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