This antibody recognises Methotrexate, a drug originally manufactured as a chemotherapeutic agent for the treatment or a number of cancers. Methotrexate also acts as a disease-modifying anti-rheumatic drug used for the treatment of autoimmune conditions such as rheumatoid arthritis, Chron's disease and vasculitis.Sheep anti methotrexate antibody exhibits the following cross reactivities with related compounds:-Aminopterin18% Folic acid<0.01% Dyhydrofolic acid<0.01% Tetrahydrofolic acid<0.01% N-5-Methyltetrahydrofolic acid<0.01% Folinic acid<0.01% N-(p-Aminobenzoyl)-L-glutamic acid<0.01%
Applications
ELISA
Reactivity
Species Independent
Immunogen
Methotrexate (4-amino-10-methylpteroyl-L-glutamic acid) conjugated via the carboxyl groups of the glutamic acid residue to Keyhole Limpet Haemocyanin.
Host
Sheep
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Purity
Serum.
Product Form
Liquid
Formulation
Supplied as serum with <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Sheep anti methotrexate antibody recognizes Methotrexate, a drug originally manufactured as a chemotherapeutic agent for the treatment or a number of cancers. Methotrexate also acts as a disease-modifying anti-rheumatic drug used for the treatment of autoimmune conditions such as rheumatoid arthritis, Chron's disease and vasculitis.Sheep anti methotrexate antibody exhibits the following cross reactivities with related compounds:-Aminopterin18%Folic acid<0.01%Dyhydrofolic acid<0.01%Tetrahydrofolic acid<0.01%N-5-Methyltetrahydrofolic acid<0.01%Folinic acid<0.01%N-(p-Aminobenzoyl)-L-glutamic acid<0.01%
