Anti-MHC Class I Monomorphic Antibody [41.17] (A278743)

Anti-MHC Class I Monomorphic Antibody [41.17]

Mouse monoclonal [41.17] antibody to MHC Class I Monomorphic.

This antibody recognises a monomorphic determinant on the class I MHC. The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. Ovine MHC class I molecules are expressed at varying levels on the majority of nucleated cells. Mouse anti Sheep MHC Class I antibody, clone 41.17 immunoprecipitates a band of ~44 kDa under reducing conditions and has also been reported to react with paraffin-embedded material following alcohol fixation.

IP, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:50 - 1:100, Use 10µl of the suggested working dilution to label 1 x 10⁶ cells in 100µl

Sheep, Bovine

Sheep lymphocytes.

Mouse

Monoclonal

41.17

IgG1

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Sheep MHC Class I antibody, clone 41.17 recognizes a monomorphic determinant on the class I MHC. The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. Ovine MHC class I molecules are expressed at varying levels on the majority of nucleated cells.Mouse anti Sheep MHC Class I antibody, clone 41.17 immunoprecipitates a band of ~44 kDa under reducing conditions and has also been reported to react with paraffin-embedded material following alcohol fixation.