Anti-MHC Class II DQ Antibody [2C4] (A279197)

Anti-MHC Class II DQ Antibody [2C4]

Mouse monoclonal [2C4] antibody to MHC Class II DQ.

This antibody recognises the class II RLA-DQ molecule. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rabbits, this complex is referred to as the rabbit leukocyte antigen (RLA) region. There are 3 major MHC class II proteins encoded by the RLA which are RLA DP, RLA DQ and RLA DR.recognises the RLA DQ molecule, expressed by antigen presenting cells, B cells and monocytes. Mouse anti rabbit MHC class II monoclonal antibody, clone 2C4 is able to significantly inhibit the mixed lymphocyte reaction. Immunoprecipitation with the antibody yields three bands of molecular weights 28, 31 and 35 kDa.

IP, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:25 - 1:200, Use 10µl of the suggested working dilution to label 10⁶ cells or 100µl whole blood

Rabbit

Rabbit spleen cells.

Mouse

Monoclonal

2C4

IgG2a

Protein A affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti rabbit MHC class II monoclonal antibody, clone 2C4 recognizes the class II RLA-DQ molecule. The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In rabbits, this complex is referred to as the rabbit leukocyte antigen (RLA) region. There are 3 major MHC class II proteins encoded by the RLA which are RLA DP, RLA DQ and RLA DR.Mouse anti rabbit MHC class II recognizes the RLA DQ molecule, expressed by antigen presenting cells, B cells and monocytes.Mouse anti rabbit MHC class II monoclonal antibody, clone 2C4 is able to significantly inhibit the mixed lymphocyte reaction. Immunoprecipitation with the antibody yields three bands of molecular weights 28, 31 and 35 kDa.