Anti-MHC Class II H-2I-Ak/D/B/Q/R Antibody [ER-TR3] (A280381)

Anti-MHC Class II H-2I-Ak/D/B/Q/R Antibody [ER-TR3]

Rat monoclonal [ER-TR3] antibody to MHC Class II H-2I-Ak/D/B/Q/R.

This antibody recognises a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, d, b, q and r. Mouse strains with the haplotypes s and f are not recognized by this antibody. Mouse MHC class II antigens are expressed by dendritic cells, B cells and macrophages. In thymus tissues, clone ER-TR3 stains cortical and medullary stromal cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.

Flow Cytometry, IHC-Fr

Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl

Mouse

Isolated C3H thymic stromal cells.

Rat

Monoclonal

ER-TR3

IgG2b

Protein G affinity chromatography of tissue culture supernatant.

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rat anti Mouse MHC Class II H-2I-Ak/D/B/Q/R antibody, clone ER-TR3 recognizes a polymorphic determinant of the mouse H-2I-A MHC class II antigen, reacting with haplotypes k, d, b, q and r. Mouse strains with the haplotypes s and f are not recognized by this antibody.Mouse MHC class II antigens are expressed by dendritic cells, B cells and macrophages. In thymus tissues, clone ER-TR3 stains cortical and medullary stromal cells.The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In mice, this complex is referred to as the H-2 region.