Anti-MHC Class II Monomorphic Antibody [IL-A21] (PE) (A280727)

Anti-MHC Class II Monomorphic Antibody [IL-A21] (PE)

Mouse monoclonal [IL-A21] antibody to MHC Class II Monomorphic (PE).

This antibody recognises a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ. Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection.

Flow Cytometry: Neat, Use 10µl of the suggested working dilution to label 1x10⁶ cells in 100µl.

Bovine

Mouse

Monoclonal

IL-A21

IgG2a

Protein G affinity chromatography of tissue culture supernatant.

Reconstitution dependent.

Lyophilized

Reconstitute with 1 ml of distilled water.

Supplied in Phosphate Buffered Saline with 1% BSA, 5% Sucrose, and 0.09% Sodium Azide.

Lyophilized: Store at 4°C. Reconstituted: Store undiluted at 4°C. Do not freeze! This product is photosensitive and should be protected from light. Should this product contain a precipitate we recommend microcentrifugation before use.

Mouse anti Bovine MHC Class II Monomorphic antibody, clone IL-A21 recognizes a monomorphic epitope within the bovine MHC II cell surface antigen. Clone IL-A21 is reported to react with an epitope which is common to both BoLA DR and DQ  (Howard et al.1997).Expression of MHC II molecules have been demonstrated on bovine B cells, activated T cells, alveolar macrophages, monocytes and mammary and bronchial epithelial cells. Clone IL-A21 is reported to inhibit T cell proliferation following FMDV infection (Collen et al. 1991).

This product is for research use only. It is not intended for diagnostic or therapeutic use.