Mouse monoclonal [26] antibody to Myelin Basic Protein.
Specificity
This antibody recognises an epitope between amino acids 67 and 74 of human myelin basic protein. Also expected to recognize isoforms 1 and 2 (UniProt: P02686). The N-terminal region of MBP is highly conserved and this clone is expected to be broadly species cross reactive for isoforms maintaining the N-terminal region.
Applications
IHC-Fr
Reactivity
Human
Immunogen
Human myelin basic protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
26
Isotype
IgG1
Conjugate
Unconjugated
Concentration
Lot Specific
Purity
Tissue Culture Supernatant.
Product Form
Liquid
Formulation
Supplied as tissue culture supernatant with 0.1M Tris/HCl, foetal calf serum and <0.1% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Human myelin basic protein is also known as MBP, Myelin A1 protein or Myelin membrane encephalitogenic protein. MBP is a 304 amino acid ~33 kDa abundant component of the myelin membrane. There are 6 potential isoforms of MBP generated by alternative splicing, 4 of which lack the N-terminal region containing the immunogen sequence.
Synonyms
MBP, Myelin A1 protein, Myelin membrane encephalitogenic protein