Anti-MZF1 Antibody [PCRP-MZF1-1E8] (A315358)

Anti-MZF1 Antibody [PCRP-MZF1-1E8]

Mouse monoclonal [PCRP-MZF1-1E8] antibody to MZF1.

Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.

Flow Cytometry, IF, IHC-P

HeLa or U87 cells. Ubiquitous tissue expression.

Flow Cytometry: 1-2 µg/million cells, IF: 1-2 µg/ml, IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 37-128) of human MZF1 protein.

Mouse

Monoclonal

PCRP-MZF1-1E8

Protein A/G chromatography.

200 µg/ml

82.05 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

MZF, MZF-1, Zinc finger and SCAN domain-containing protein 6, Zinc finger protein 42, ZNF42, ZSCAN6