This antibody recognises nuclear factor of activated T-cells, cytoplasmic 2.NFATC2 is a 100 kDa member of the nuclear factor of activated T cells (NFAT) family normally located to the cytosol. However, upon T cell receptor (TCR) stimulation NFATC2 is translocated to the nucleus where it becomes a member of the Nuclear factors of activated T cells transcription complex. The T cells transcription complex plays a vital role in inducing gene transcription during the immune response.
Applications
IP, WB
Dilutions
IP: 10 µl per IP, WB: 1:500 - 1:2,000
Reactivity
Human
Immunogen
A peptide derived from within the N-terminus of human NFATC2.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human NFATC2 antibody recognizes nuclear factor of activated T-cells, cytoplasmic 2.NFATC2 is a 100 kDa member of the nuclear factor of activated T cells (NFAT) family normally located to the cytosol. However, upon T cell receptor (TCR) stimulation NFATC2 is translocated to the nucleus where it becomes a member of the Nuclear factors of activated T cells transcription complex. The T cells transcription complex plays a vital role in inducing gene transcription during the immune response (Rao et al. 1997).
