Recombinant Anti-NKX2.8 Antibody [NKX28/3233R] (A248693)

Anti-NKX2.8 Antibody [NKX28/3233R]

Recombinant rabbit monoclonal [NKX28/3233R] antibody to NKX2.8.

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Human

Recombinant fragment, around amino acids 10-123, of human NKX2.8 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

NKX28/3233R

IgG

200 µg/ml

26 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-NKX2.8 Antibody [NKX28/3233R] - BSA and Azide free (A251875).

Homeobox protein NK-2 homolog H, Homeobox protein Nkx-2.8, NKX-2.8, NKX2-8, NKX2G, NKX2H