Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (A285915)

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This product is discontinued

Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (A285915) has been discontinued and is no longer available.

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Specifications

Name

Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488)

Description

Mouse monoclonal [PAC-1] antibody to PAC-1 (Alexa Fluor® 488).

Specificity

This antibody recognizes an extracellular activation-induced conformational epitope PAC-1 on CD41/CD61 complex (gpIIb/IIIa), also known as integrin alpha IIb beta 3, a receptor which mediates platelet aggregation.

Applications

ICC, Flow Cytometry

Dilutions

Flow Cytometry: The reagent is designed for analysis of human blood cells using 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension.

Reactivity

Human

Immunogen

Human platelets.

Host

Mouse

Clonality

Monoclonal

Clone ID

PAC-1

Isotype

IgM

Light Chains

kappa

Conjugate

Alexa Fluor® 488

Excitation: 490nm, Emission: 525nm

Formulation

Supplied in Tris Buffered Saline, pH 8.0, with 15 mM Sodium Azide.

Storage

Store in the dark at 2-8°C. Do not freeze!

Synonyms

C21-LRP, C21LRP, Chromosome 21 leucine-rich protein, Down syndrome critical region protein 2, DSCR2, PAC1, Proteasome assembly chaperone 1

Disclaimer

This product is for research use only. It is not intended for diagnostic or therapeutic use.

Scientific Validation DataValidation Data (2)

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Flow Cytometry - Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (A285915)

Flow cytometry surface staining pattern of human PHA stimulated peripheral whole blood stained with Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (4 µl reagent / 100 µl of peripheral whole blood).

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Flow Cytometry - Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (A285915)

Separation of human thrombocytes (red-filled) from lymphocytes (black-dashed) in flow cytometry analysis (surface staining) of human PHA stimulated peripheral whole blood stained with Anti-PAC-1 Antibody [PAC-1] (Alexa Fluor® 488) (4 µl reagent / 100 µl of peripheral whole blood).