Recombinant Anti-PD-L1 Antibody [ZR3] - BSA and Azide free (A316879)

Anti-PD-L1 Antibody [ZR3] - BSA and Azide free

Recombinant rabbit monoclonal [ZR3] antibody to PD-L1.

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Human placenta, spleen or tonsil tissue.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 190-290) of human CD274 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

ZR3

IgG

Protein A/G chromatography.

1 mg/ml

37-50 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

B7 homolog 1, B7-H1, B7H1, CD274, PDCD1L1, PDCD1LG1, PDL1, Programmed cell death 1 ligand 1