Recombinant Anti-PD1 Antibody [PDCD1/4231R] (A315489)

Anti-PD1 Antibody [PDCD1/4231R]

Recombinant rabbit monoclonal [PDCD1/4231R] antibody to PD1.

PDCD-1 (programmed cell death-1 protein), also designated CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD-1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD-1 is expressed by few B-cells, so anti-PDCD-1 may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma. In addition, PDCD-1 expression provides evidence that angioimmunoblastic lymphoma is a neoplasm derived from germinal center-associated T-cells.

ELISA, IHC-P

Human tonsil, lymph node or appendix.

IHC: 1-2 µg/ml

Human

Recombinant fragment corresponding to extracellular domain of human PDCD1 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

PDCD1/4231R

IgG

Protein A/G chromatography.

200 µg/ml

55 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

CD279, CD279 antigen, hPD 1, hPD l, hPD-1, hSLE1, PD 1, PD-1, PDCD 1, PDCD1, PDCD1_HUMAN, Programmed cell death 1, Programmed cell death 1 protein, Programmed cell death protein 1, Protein PD 1, Protein PD-1, SLEB2, Systemic lupus erythematosus susceptibility 2