Anti-PDGFR alpha Antibody [PDGFRA/7407] - BSA and Azide free (A316877)

Anti-PDGFR alpha Antibody [PDGFRA/7407] - BSA and Azide free

Mouse monoclonal [PDGFRA/7407] antibody to PDGFR alpha.

Platelet-derived growth factor (PDGF) is a mitogen for mesenchyme- and glia-derived cells. PDGF consists of two chains, A and B, which dimerize to form functionally distinct isoforms, PGDF-AA, PDGF-AB and PDGF-BB. These three isoforms bind with different affinities to two receptor types, PDGFR-a and - gene with the Tel gene is linked to chronic myelomonocytic leukemia (CMML), a myelodysplastic syndrome, and demonstrates the oncogenic potential of the PDGF receptors.

Primary, metastatic colon tumors and normal colon. Tumors may express a different isoform to that found in normal tissue.

IHC: 1-2 µg/ml

Human

Recombinant fragment (around Amino Acids 1-200) of human PDGFRA protein. The exact sequence is proprietary.

Mouse

Monoclonal

PDGFRA/7407

IgG1

Protein A/G chromatography.

1 mg/ml

170 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, PDGF-R-alpha, PDGFR-2, PDGFR-alpha, PDGFR2, PDGFRA, Platelet-derived growth factor alpha receptor, Platelet-derived growth factor receptor 2, Platelet-derived growth factor receptor alpha, RHEPDGFRA