This antibody recognises PIDD also known as p53-induced death domain protein 1. PIDD is a scaffold protein that interacts with both pro-death and pro-survival proteins following DNA damage. PIDD undergoes cleavage producing several smaller fragments which bind to either pro-death or pro-survival signaling molecules.
Applications
WB
Dilutions
WB: 1:500 - 1:1,000
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant human PIDD.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Molecular Weight
Approximately 110 kDa in cell lysates under reducing conditions
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 50% Glycerol and 0.02% Sodium Azide.
Storage
Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.
General Notes
Rabbit anti PIDD antibody recognizes PIDD also known as p53-induced death domain protein 1. PIDD is a scaffold protein that interacts with both pro-death and pro-survival proteins following DNA damage. PIDD undergoes cleavage producing several smaller fragments which bind to either pro-death or pro-survival signaling molecules.
Synonyms
Leucine-rich repeat and death domain-containing protein, p53-induced death domain-containing protein 1, PIDD
