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Anti-PKC iota Antibody [PRKCI/4912] (A277764)

Mouse monoclonal [PRKCI/4912] antibody to PKC iota for IHC-P.

Alternative Formats and ConjugatesAlternative Formats

Shipping Information

$40
Dispatched from St. Louis, MO.
Lead Time: 5-8 business days.
Name
Anti-PKC iota Antibody [PRKCI/4912]
Description
Mouse monoclonal [PRKCI/4912] antibody to PKC iota.
Specificity
Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. PKCs were originally identified as serine/threonine protein kinases whose activity was dependent on calcium and phospholipids. Diacylglycerols (DAG) and tumor promoting phorbol esters bind to and activate PKC. PKCs can be subdivided into at least two major classes, including conventional (c) PKC isoforms (α, βI, βII and γ) and novel (n) PKC isoforms ( L, , Ã·, , , l/i, m and n). Patterns of expression for each PKC isoform differ among tissues and PKC family members exhibit clear differences in their cofactor dependencies. For instance, the kinase activities of PKC L and are independent of Ca2+. On the other hand, most of the other PKC members possess phorbol ester-binding activities and kinase activities.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human
Immunogen
Recombinant fragment, around amino acids 100-300, of human PKC iota. The exact sequence is proprietary.
Host
Mouse
Clonality
Monoclonal
Clone ID
PRKCI/4912
Isotype
IgG2b
Light Chains
kappa
Conjugate

Unconjugated

Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
68 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
General Notes
This monoclonal antibody is also available in a different formulation without BSA and Sodium Azide - Anti-PKC iota Antibody [PRKCI/4912] - BSA and Azide free (A278352).
Synonyms
aPKC-lambda/iota, Atypical protein kinase C-lambda/iota, DXS1179E, nPKC-iota, PRKC-lambda/iota, PRKCI, Protein kinase C iota type
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.
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99.9% Relevancy Score
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99.3% Relevancy Score
98.9% Relevancy Score
96.8% Relevancy Score
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