Anti-Prekallikrein Heavy Chain Antibody [13G11] - BSA and Azide free (A304203)

Anti-Prekallikrein Heavy Chain Antibody [13G11] - BSA and Azide free

Mouse monoclonal [13G11] antibody to Prekallikrein Heavy Chain.

Recognizes two variants of Prekallikrein in human plasma (88kDa and 85kDa) and its activation products Kallikrein, the complexes formed by Kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and antithrombin III, and 45kDa Prekallikrein/Kallikrein fragments. The epitope is located on the Prekallikrein/Kallikrein heavy chain and is involved in the interaction between Prekallikrein and Factor XIIa. Inhibits Prekallikrein activation in human and rhesus plasmas by ~60- 80% and 55%, respectively. Does not cross-react with tissue kallikrein.

WB, ELISA

WB: 1-5 µg/ml, ELISA: 5-10 µg/ml

Human, Chimpanzee, Rhesus Monkey, Baboon

Purified human Prekallikrein.

Mouse

Monoclonal

13G11

IgG1

Protein A chromatography.

Lot Specific

85 kDa / 88 kDa

Liquid

Supplied in Phosphate Buffered Saline, pH 7.4.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

For ELISA use with Prekallikrein sample bound to ELISA plates.