Anti-Pro IL-33 Antibody (A283165)

Anti-Pro IL-33 Antibody

Rabbit polyclonal antibody to Pro IL-33.

This antibody recognises human pro-interleukin-33 (pro-IL-33). Pro-IL-33 is further processed into its mature secreted form, IL-33.IL-33, a cytokine formerly known as NF-HEV or nuclear factor from high endothelieal venules, belongs to the IL-1 super family which signals through interaction with the ST2 and Toll-interleukin 1 (IL-1) receptors, and is known to act as an immunoregulator of T helper 2 (Th2) cell cytokine synthesis.IL-33 is abundantly expressed in high endothelial venules found in tonsils, peyers patches and mesenteric lymph nodes.

WB, IF

IF: 20 µg/ml, WB: 1.0 - 2 µg/ml, This product does not require protein digestion pre-treatment of paraffin sections. This product does not require antigen retrieval using heat treatment prior to staining of paraffin sections.

Human

A peptide corresponding to 19 amino acids near the N-terminus of Genbank accession No. NP_254274.

Rabbit

Polyclonal

IgG

1 mg/ml

Approximately 36 kDa in human lymph node cell lysates.

Liquid

Supplied in Phosphate Buffered Saline with 0.02% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Rabbit anti Human pro-interleukin-33 antibodyrecognises human pro-interleukin-33 (pro-IL-33). Pro-IL-33 is further processed into its mature secreted form, IL-33.IL-33, a cytokine formerly known as NF-HEV or nuclear factor from high endothelieal venules, belongs to the IL-1 super family which signals through interaction with the ST2 and Toll-interleukin 1 (IL-1) receptors, and is known to act as an immunoregulator of T helper 2 (Th2) cell cytokine synthesis.IL-33 is abundantly expressed in high endothelial venules found in tonsils, peyers patches and mesenteric lymph nodes.