Anti-proBNP Antibody [18H5] (A279063)

Anti-proBNP Antibody [18H5]

Mouse monoclonal [18H5] antibody to proBNP .

This antibody recognises the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP. NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.

WB, Immunoassay, ELISA

Human

Amino acids 13-27 of NT-proBNP.

LLLFLHLAFLGGRSH

Mouse

Monoclonal

18H5

IgG1

Protein A affinity chromatography of tissue culture supernatant.

Approximately 9 kDa when using recombinant NT-proBNP

Liquid

Supplied in Phosphate Buffered Saline with <0.1% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Human BNP Prohormone (N-Terminal) antibody, clone 18H5 detects the amino-terminal fragment of pro-brain natriuretic peptide (amino acids 13-20), also known as NT-proBNP, a cleavage product during the proteolytic activation of BNP. NT-proBNP is a secreted protein which is a member of the natriuretic peptide family, which is predominantly secreted from the cardiac ventricles in response to volume and pressure overload. NT-proBNP is more stable than BNP in serum, and has become a useful biomarker of heart failure.

Brain natriuretic factor prohormone, Gamma-brain natriuretic peptide, Iso-ANP, Natriuretic peptides B, NPPB, preproBNP