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Anti-Reticulum Cells Antibody [ED11] (A280323)

This product is discontinued

Anti-Reticulum Cells Antibody [ED11] (A280323) has been discontinued and is no longer available.

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Name
Anti-Reticulum Cells Antibody [ED11]
Description
Mouse monoclonal [ED11] antibody to Reticulum Cells.
Specificity
This antibody recognises reticular elements in the T cell areas and B cell follicles of spleen, lymph nodes, Peyer's patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed throughout the cortex capsule, the medulla is negative. In non-lymphoid organs positivity is seen only in reticular elements of the small intestine. No staining of liver, lung, skin, kidney, brain, pancreas or heart is seen.recognises complement factor C3. In vivo Mouse anti Rat reticulum cells antibody, clone ED11 blocks immune complex trapping on follicular dendritic cells.
Applications
IHC-Fr, ELISA, Flow Cytometry
Dilutions
IHC-Fr 1: 1:100 - 1:300
Reactivity
Rat
Immunogen
Rat spleen cell homogenate.
Host
Mouse
Clonality
Monoclonal
Clone ID
ED11
Isotype
IgG1
Conjugate

Unconjugated

Concentration
1 mg/ml
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Mouse anti Rat reticulum cells antibody, clone ED11 recognizes reticular elements in the T cell areas and B cell follicles of spleen, lymph nodes, Peyer's patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed throughout the cortex capsule, the medulla is negative. In non-lymphoid organs positivity is seen only in reticular elements of the small intestine. No staining of liver, lung, skin, kidney, brain, pancreas or heart is seen.Mouse anti Rat reticulum cells antibody, clone ED11 recognizes complement factor C3. In vivo Mouse anti Rat reticulum cells antibody, clone ED11 blocks immune complex trapping on follicular dendritic cells (Van den Berg et al. 1992).
Disclaimer
This product is for research use only. It is not intended for diagnostic or therapeutic use.