General Notes
Mouse anti Rat reticulum cells antibody, clone ED11 recognizes reticular elements in the T cell areas and B cell follicles of spleen, lymph nodes, Peyer's patches, bronchus and gut associated lymphoid tissues (BALT and GALT). In the thymus a reticular pattern is observed throughout the cortex capsule, the medulla is negative. In non-lymphoid organs positivity is seen only in reticular elements of the small intestine. No staining of liver, lung, skin, kidney, brain, pancreas or heart is seen.Mouse anti Rat reticulum cells antibody, clone ED11 recognizes complement factor C3. In vivo Mouse anti Rat reticulum cells antibody, clone ED11 blocks immune complex trapping on follicular dendritic cells (Van den Berg et al. 1992).