Recombinant Anti-Sarcomeric Actinin alpha 2 Antibody [ACTN2/7039R] - BSA and Azide free (A278672)

Anti-Sarcomeric Actinin alpha 2 Antibody [ACTN2/7039R] - BSA and Azide free

Recombinant rabbit monoclonal [ACTN2/7039R] antibody to Sarcomeric Actinin alpha 2.

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In non-muscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene.

IHC-P: 1-2 µg/ml

Human

Recombinant fragment, around amino acids 557-692, of human ACTN2 protein. The exact sequence is proprietary.

Rabbit

Monoclonal

ACTN2/7039R

kappa

Protein A/G chromatography.

1 mg/ml

103 kDa

Liquid

Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.

Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

This monoclonal antibody is also available in a different formulation with BSA and Sodium Azide - Anti-Sarcomeric Actinin alpha 2 Antibody [ACTN2/7039R] (A278084).