Anti-SIRP alpha Antibody [OX-41] (A281454)

Anti-SIRP alpha Antibody [OX-41]

Mouse monoclonal [OX-41] antibody to SIRP alpha.

This antibody recognises rat CD172a, also known as Signal regulatory protein (SIRP). CD172a is expressed selectively by myeloid cells and by neurons.MRC OX-41 binds to a different epitope on SIRP than ED9. Mouse anti Rat CD172a antibody, clone OX-41 does not completely block the interaction of CD172a - CD47.

WB, IHC-P, Flow Cytometry, IHC-Fr

Flow Cytometry: 1:100 for 0.1 mg, 1 mg, 1:10 for 0.25 mg - 1:200 for 0.1 mg, 1 mg, 1:50 for 0.25 mg, Use 10µl of the suggested working dilution to label 10⁶ cells in 100µl.

Rat

Rat peritoneal macrophages.

Mouse

Monoclonal

OX-41

IgG2a

1 mg/ml

Liquid

Supplied in Phosphate Buffered Saline with 0.09% Sodium Azide.

Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.

Mouse anti Rat CD172a antibody, clone OX-41 recognizes rat CD172a, also known as Signal regulatory protein (SIRP). CD172a is expressed selectively by myeloid cells and by neurons.MRC OX-41 binds to a different epitope on SIRP than ED9. Mouse anti Rat CD172a antibody, clone OX-41 does not completely block the interaction of CD172a - CD47 (Vernon-Wilson et al. 2000).

BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, CD172a, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MFR, MyD-1 antigen, MYD1, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, SIRP, SIRPA, Tyrosine-protein phosphatase non-receptor type substrate 1