This antibody recognises SET (suppressor of variegation, enhancer of zeste, trithorax) and MYND (myeloid-nervy-DEAF-1) domain-containing protein 3.SMYD3 is a lysine methyltransferase that specifically methylates H3K4 and H4K5. As part of an RNA polymerase complex, SMYD3 is involved in transcriptional regulation. SMYD3 has also been shown to play a role in the regulation of some cancers.
Applications
WB
Dilutions
WB: 1:500 - 1:1,000
Reactivity
Human
Immunogen
A peptide derived from within human SMYD3.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human SMYD3 antibody recognizes SET (suppressor of variegation, enhancer of zeste, trithorax) and MYND (myeloid-nervy-DEAF-1) domain-containing protein 3.SMYD3 is a lysinemethyltransferase that specifically methylates H3K4 and H4K5. As part of an RNA polymerase complex, SMYD3 is involved in transcriptional regulation.SMYD3 has also been shown to play a role in the regulation of some cancers (Van Aller et al. 2012) (Liu et al. 2015).
Synonyms
Histone-lysine N-methyltransferase SMYD3, SET and MYND domain-containing protein 3, Zinc finger MYND domain-containing protein 1, ZMYND1, ZNFN3A1
