Anti-Soluble IL-4R alpha Antibody - BSA and Azide free (A283751)

Anti-Soluble IL-4R alpha Antibody - BSA and Azide free

Rabbit polyclonal antibody to Soluble IL-4R alpha.

This antibody recognises soluble interleukin-4 receptor subunit alpha (sIL-4RA), also known as IL-4 binding protein. sIL-4RA is the naturally occurring soluble form of IL-4RA, a type I receptor which is a functional receptor of IL-4 and IL-13. sIL-4RA is present in biological fluids and contains only the extracellular portion of IL-4RA. It is produced by proteolytic shedding of the membrane bound form or through alternative splicing of the gene. Like IL-4RA, the soluble form is able to bind IL-4, which effectively inhibits the biological function of IL-4.

WB, ELISA

ELISA: 0.5 µg/ml - 2.0 µg/ml, WB: 0.1 µg/ml - 0.2 µg/ml

Human

CHO cell-derived recombinant soluble interleukin-4 receptor subunit alpha (sIL-4RA) corresponding to 209 amino acid residues of the extracellular domain of IL-4RA.

Rabbit

Polyclonal

IgG

Lyophilized

Reconstitute with 0.1 ml of distilled water.

Supplied in Phosphate Buffered Saline.

Lyophilized: Store at -20°C. Reconstituted: Store undiluted at -20°C, avoid freeze / thaw cycles. Storage in frost free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti Human sIL-4 receptor alpha antibody, recognizes soluble interleukin-4 receptor subunit alpha (sIL-4RA), also known as IL-4 binding protein. sIL-4RA is the naturally occurring soluble form of IL-4RA, a type I receptor which is a functional receptor of IL-4 and IL-13 (Henderson et al. 2000). sIL-4RA is present in biological fluids and contains only the extracellular portion of IL-4RA (Andrews et al. 2006). It is produced by proteolytic shedding of the membrane bound form or through alternative splicing of the gene. Like IL-4RA, the soluble form is able to bind IL-4, which effectively inhibits the biological function of IL-4 (Silvestri et al. 2006).