Mouse monoclonal [PCRP-SOX12-1E4] antibody to SOX22.
Specificity
Sox genes comprise a family of genes that are related to the mammalian sex determining gene SRY. These genes similarly contain sequences that encode for the HMG-box domain, which is responsible for the sequence-specific DNA-binding activity. Sox genes encode putative transcriptional regulators implicated in the decision of cell fates during development and the control of diverse developmental processes. The highly complex group of Sox genes cluster at a minimum of 40 different loci that rapidly diverged in various animal lineages. At present 30 Sox genes have been identified, and members of this family have been shown to be conserved during evolution and to play key roles during animal development. Some are involved in human diseases, including sex reversal.
Applications
Flow Cytometry
Positive Control
HeLa or U87 cells.
Dilutions
Flow Cytometry: 1-2 µg/million cells
Reactivity
Human
Immunogen
Recombinant fragment (around Amino Acids 31-110) of human SOX12 protein.
Host
Mouse
Clonality
Monoclonal
Clone ID
PCRP-SOX12-1E4
Isotype
IgG1
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
200 µg/ml
Molecular Weight
34.12 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline with 0.05% BSA and 0.05% Sodium Azide.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Synonyms
Protein SOX-22, SOX12, Transcription factor SOX-12
