Anti-STAT2 (phospho Tyr690) Antibody (A283679)

Anti-STAT2 (phospho Tyr690) Antibody

Rabbit polyclonal antibody to STAT2 (phospho Tyr690).

This antibody recognises STAT2, also known as p113 when phosphorylated at tyrosine 690. STAT2 is a member of the STAT family of transcription factors. Upon ligand binding receptor associated kinases phosphorylate STATs causing them to dimerize and translocate to the nucleus. STAT2 forms a heterodimer with STAT1 where promotes transcription at interferon-sensitive response elements. Phosphorylation of STAT2 at tyrosine 690 by JAKs promotes the dimerization with STAT1.

WB: 1:500 - 1:1,000

Human

Phospho-specific peptide corresponding to residues surrounding Tyr690 of human STAT2.

Rabbit

Polyclonal

IgG

Lot Specific

Liquid

Supplied in Phosphate Buffered Saline with 0.05% ProClin 300 and 50% Glycerol.

Store undiluted at -20°C. Storage in frost free freezers is not recommended. Avoid freeze-thaw cycles. Should this product contain a precipitate we recommend microcentrifugation before use.

Rabbit anti STAT2 (pTyr690) antibody recognizes STAT2, also known as p113 when phosphorylated at tyrosine 690. STAT2 is a member of the STAT family of transcription factors. Upon ligand binding receptor associated kinases phosphorylate STATs causing them to dimerize and translocate to the nucleus. STAT2 forms a heterodimer with STAT1 where promotes transcription at interferon-sensitive response elements. Phosphorylation of STAT2 at tyrosine 690 by JAKs promotes the dimerization with STAT1.

p113, Signal transducer and activator of transcription 2