Anti-Steroidogenic Factor 1 Antibody [NR5A1/4368R] - BSA and Azide free
Description
Recombinant rabbit monoclonal [NR5A1/4368R] antibody to Steroidogenic Factor 1.
Specificity
Steroidogenic Factor 1 (SF-1) is considered an orphan nuclear receptor that belongs to subfamily 5. It was found to be a regulator of steroidogenic enzyme gene expression. Oxysterols are suggested as its ligands. It is expressed in all steroidogenic tissues, including the adrenal cortex, testicular Sertoli cells, and Leydig cells, ovarian theca, hypothalamus, and anterior pituitary. SF-1 plays an important role in adrenal and gonadal development.SF-1 is highly valuable marker to determine the adrenocortical origin of an adrenal mass.
Applications
IHC-P
Dilutions
IHC-P: 1-2 µg/ml
Reactivity
Human, Rat
Immunogen
Recombinant fragment corresponding to human SF-1 protein. The exact sequence is proprietary.
Host
Rabbit
Clonality
Monoclonal
Clone ID
NR5A1/4368R
Isotype
IgG
Light Chains
kappa
Conjugate
Unconjugated
Purification
Protein A/G chromatography.
Concentration
1 mg/ml
Molecular Weight
53 kDa
Product Form
Liquid
Formulation
Supplied in 10mM Phosphate Buffered Saline; without Sodium Azide and carrier free.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal oncocytoma tissue using Anti-Steroidogenic Factor 1 Antibody [NR5A1/4368R].
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