This antibody recognises transcription factor 7.TCF7 is a transcription factor involved in the regulation of the expression of several genes located in the cells of the liver. TCF7 has been shown to promote proliferation in glioblastoma multiforme cells through upregulation of c-Myc and acts as an unfavorable prognostic marker of glioblastoma multiforme.
Applications
WB
Dilutions
WB: 1:500 - 1:1,000
Reactivity
Human
Immunogen
A peptide derived from within the N-terminus of human TCF7.
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Conjugate
Unconjugated
Concentration
Lot Specific
Product Form
Liquid
Formulation
Supplied in Phosphate Buffered Saline with 0.035% Sodium Azide and 30% Glycerol.
Storage
Shipped at ambient temperature. Upon delivery aliquot and store at -20°C. When thawed, aliquot the sample as needed. Short term (up to 4 weeks): store at 4°C. Long term: store at -20°C. Avoid freeze / thaw cycles. Storage in frost free freezers is not recommended.
General Notes
Rabbit anti Human TCF7 antibody recognizes transcription factor 7.TCF7 is atranscription factorinvolved in the regulation of the expression of several genes located in the cells of the liver (Courtois et al. 1987). TCF7 has been shown to promote proliferation in glioblastoma multiforme cells through upregulation of c-Myc and acts as an unfavorable prognostic marker of glioblastoma multiforme (Su et al. 2018).